BDBM50143775 3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-5-methyl-thiophene-2-carboxylic acid (4,6-diacetyl-3-hydroxy-2-propyl-phenyl)-amide::CHEMBL304860

SMILES CCCc1c(O)c(cc(C(C)=O)c1NC(=O)c1sc(C)cc1S(=O)(=O)Nc1onc(C)c1Cl)C(C)=O

InChI Key InChIKey=VYWDHFQLTPQODD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143775   

TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143775(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-5-met...)
Affinity DataIC50: 12.4nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed