BDBM50143598 6-[(4-Chloro-phenyl)-imidazol-1-yl-methyl]-4-phenyl-1H-quinolin-2-one::CHEMBL55431

SMILES Clc1ccc(cc1)C(c1ccc2[nH]c(=O)cc(-c3ccccc3)c2c1)n1ccnc1

InChI Key InChIKey=RHBIJCCFGBZWIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143598   

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143598(6-[(4-Chloro-phenyl)-imidazol-1-yl-methyl]-4-pheny...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against farnesyltransferase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed