BDBM50143332 (S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z)-ylidene]-propyl}-pyrrolidine-2-carboxylic acid [(S)-1-carbamoyl-2-(4-hydroxy-phenyl)-ethyl]-amide::CHEMBL57816

SMILES CC\C(N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)=C1\N=C(OC1=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=PNPVAJCOFSBWBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50143332   

TargetMethionine--tRNA ligase, cytoplasmic(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143332((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human methionyl-tRNA synthetase (fMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143332((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMethionine--tRNA ligase, cytoplasmic(Human)
Arqule

Curated by ChEMBL
LigandPNGBDBM50143332((S)-1-{1-[2-(2,4-Dichloro-phenyl)-5-oxo-oxazol-(4Z...)
Affinity DataIC50: 180nMAssay Description:Inhibition of Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed