BDBM50143121 3-Cyclopropyl-6-(6-methyl-pyridin-2-ylmethoxy)-[1,2,4]triazolo[3,4-a]phthalazine::CHEMBL296383

SMILES Cc1cccc(COc2nn3c(nnc3c3ccccc23)C2CC2)n1

InChI Key InChIKey=OBPPXGLDCMXNDT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143121   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143121(3-Cyclopropyl-6-(6-methyl-pyridin-2-ylmethoxy)-[1,...)
Affinity DataKi:  0.920nMAssay Description:Binding affinity for human GABA-A receptor alpha-5-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143121(3-Cyclopropyl-6-(6-methyl-pyridin-2-ylmethoxy)-[1,...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity for human GABA-A receptor alpha-3-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143121(3-Cyclopropyl-6-(6-methyl-pyridin-2-ylmethoxy)-[1,...)
Affinity DataKi:  9.70nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50143121(3-Cyclopropyl-6-(6-methyl-pyridin-2-ylmethoxy)-[1,...)
Affinity DataKi:  32nMAssay Description:Binding affinity for human GABA-A receptor alpha-4-beta-3-gamma-2 subunits in L(tk-) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed