BDBM50142914 CHEMBL3758199

SMILES CO[C@@H]1CN(CCCn2ccnc2)CC[C@@H]1NC(=O)c1cc(Cl)c(N)cc1OC

InChI Key InChIKey=WAKRHHOAPNHFPH-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142914   

Target5-hydroxytryptamine receptor 4(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50142914(CHEMBL3758199)
Affinity DataIC50: 1.17E+3nMAssay Description:Displacement of [3H]-GR113808 from human 5-HT4 receptor expressed in African green monkey COS7 cell membranes after 30 mins by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50142914(CHEMBL3758199)
Affinity DataIC50: 7.26E+3nMAssay Description:Inhibition of human ERG channel by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50142914(CHEMBL3758199)
Affinity DataEC50:  251nMAssay Description:Agonist activity at 5-HT4 receptor in rat esophageal thoracic muscularis mucosae assessed as carbachol-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed