BDBM50142889 Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine::CHEMBL40798::N-butyl-1-(2-chloro-2-phenylethyl)-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

SMILES CCCCNc1nc(SC)nc2n(CC(Cl)c3ccccc3)ncc12

InChI Key InChIKey=QFADNOVKNDFOQL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142889   

TargetTyrosine-protein kinase ABL1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50142889(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfany...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant Abl by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50142889(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfany...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against Src in cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50142889(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfany...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50142889(Butyl-[1-(2-chloro-2-phenyl-ethyl)-6-methylsulfany...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed