BDBM50142878 CHEMBL53193::N*2*-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,4-diamine

SMILES CNc1ncc(Cc2cc(OC)c(OC)c(OC)c2)c(N)n1

InChI Key InChIKey=LCMRPHMVLYACMM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142878   

TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50142878(N*2*-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against Mycobacterium avium dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50142878(N*2*-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50142878(N*2*-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50142878(N*2*-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibitory activity against rat dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed