BDBM50142750 CHEMBL3759252

SMILES CCOC(=O)c1c(CSc2ccccc2C)[nH]c2c1cc(O)c1ccccc21

InChI Key InChIKey=KNHZSIXYYJUGMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142750   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50142750(CHEMBL3759252)
Affinity DataIC50: 255nMAssay Description:Inhibition of 5-LOX in human intact polymorphonuclear leukocytes preincubated for 15 mins with CaCl2, A23187 measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Second University of Naples

Curated by ChEMBL
LigandPNGBDBM50142750(CHEMBL3759252)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 using arachidonic acid as substrate assessed as LTB4 formation preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2017
Entry Details Article
PubMed