BDBM50142621 CHEMBL3759292

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)NCc1ccccc1

InChI Key InChIKey=SYOVEDOWOXNOJG-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50142621   

TargetDelta-type opioid receptor(Mouse)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataEC50:  32nMAssay Description:Agonist activity at mu-opioid receptor in guinea pig ileum assessed as inhibition of electrically induced twitchesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.0310nMAssay Description:Binding affinity at mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.151nMAssay Description:Displacement of [3H]DPN from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  0.160nMAssay Description:Binding affinity at delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]DPN from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed