BDBM50142618 CHEMBL3759959

SMILES N[C@H](Cc1cccc(c1)-c1cccc(O)c1)C(O)=O

InChI Key InChIKey=KLQKIRKWYATAMF-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50142618   

TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity against recombinant rat GluA2(Q)i expressed in xenopus oocytes assessed as inhibition of L-glutamate-induced intracellular calciu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  2.40E+4nMAssay Description:Displacement of [3H]AMPA from full length rat cloned GluA2(R)o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  3.96E+4nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK3A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  5.41E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA1o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  5.47E+4nMAssay Description:Displacement of [3H]AMPA from rat cloned GluA3o receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  8.40E+4nMAssay Description:Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  1.05E+5nMAssay Description:Displacement of [3H]SYM2081 from recombinant rat GluK1(Q)1b receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50142618(CHEMBL3759959)
Affinity DataKi:  1.36E+5nMAssay Description:Displacement of [3H]SYM2081 from cloned rat GluK2(V,C,R)A receptor expressed in sf9 cells incubated for 1 to 2 hrs by liquid scintillation counting m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed