BDBM50142465 1-(3-Cyano-phenyl)-3-{3-[3-(2-fluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL43818

SMILES Fc1ccccc1CC1CCCN(CCCNC(=O)Nc2cccc(c2)C#N)C1

InChI Key InChIKey=FIHBKUQPDFXYIG-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142465   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142465(1-(3-Cyano-phenyl)-3-{3-[3-(2-fluoro-benzyl)-piper...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]eotaxin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142465(1-(3-Cyano-phenyl)-3-{3-[3-(2-fluoro-benzyl)-piper...)
Affinity DataKi:  2.24E+3nMAssay Description:Inhibition of [125I]-eotaxin binding to serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed