BDBM50142455 1-(3-Cyano-phenyl)-3-{3-[3-(2,4-difluoro-benzyl)-piperidin-1-yl]-propyl}-urea::CHEMBL42264

SMILES Fc1ccc(CC2CCCN(CCCNC(=O)Nc3cccc(c3)C#N)C2)c(F)c1

InChI Key InChIKey=QGAROWKDUWSNKV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50142455   

TargetC-C chemokine receptor type 3(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142455(1-(3-Cyano-phenyl)-3-{3-[3-(2,4-difluoro-benzyl)-p...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 3 using human [125I]eotaxin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142455(1-(3-Cyano-phenyl)-3-{3-[3-(2,4-difluoro-benzyl)-p...)
Affinity DataKi:  2.36E+3nMAssay Description:Inhibition of [125I]-eotaxin binding to serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed