BDBM50142238 CHEMBL3759201

SMILES Cc1ccc(cc1)-c1ncc(OCC2CCNCC2)cc1-c1ccc(cc1)C#N

InChI Key InChIKey=JQPWKVGXPWCDEE-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50142238   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataIC50: 8.76E+4nMAssay Description:Inhibition of recombinant human AKT for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant LSD1 by horseradish peroxidase-coupled fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataIC50: 1.34E+5nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataKi:  29nMAssay Description:Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataKi:  29nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataKi:  1.87E+4nMAssay Description:Inhibition of recombinant human MAO-B after 60 mins MAO-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50142238(CHEMBL3759201)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human MAO-A after 60 mins MAO-glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed