BDBM50142061 (2S)-2-(1-cyclohexyl-2-(furan-3-yl)-1H-benzo[d]imidazole-5-carboxamido)-3-(1H-indol-3-yl)propanoic acid::(S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carbonyl)-amino]-3-(1H-indol-3-yl)-propionic acid::2-{4-[4''-Chloro-4-(4-hydroxy-piperidine-1-carbonyl)-biphenyl-2-ylmethoxy]-2-fluoro-phenyl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid::CHEMBL353549

SMILES OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccoc1

InChI Key InChIKey=OYJUPKPIVBUVPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50142061   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061(2-{4-[4''-Chloro-4-(4-hydroxy-piperidine-1-carbony...)
Affinity DataIC50: 400nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061(2-{4-[4''-Chloro-4-(4-hydroxy-piperidine-1-carbony...)
Affinity DataIC50: 2.00E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061(2-{4-[4''-Chloro-4-(4-hydroxy-piperidine-1-carbony...)
Affinity DataIC50: 3.16E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142061(2-{4-[4''-Chloro-4-(4-hydroxy-piperidine-1-carbony...)
Affinity DataIC50: 19nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed