BDBM50142047 (S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carbonyl)-amino]-3-[5-(5H-tetrazol-5-yl)-1H-indol-3-yl]-propionic acid::CHEMBL366575

SMILES OC(=O)[C@H](Cc1c[nH]c2ccc(cc12)-c1nnn[nH]1)NC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccoc1

InChI Key InChIKey=WPRSTEIMZYUPAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142047   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: 15nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: 2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142047((S)-2-[(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazol...)
Affinity DataIC50: 2.00E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed