BDBM50142045 (S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carbonyl)-amino]-propionic acid::CHEMBL174670

SMILES CC(=O)Nc1ccc2[nH]cc(C[C@H](NC(=O)c3ccc4n(C5CCCCC5)c(nc4c3)-c3ccoc3)C(O)=O)c2c1

InChI Key InChIKey=GNSOUSOCISFCDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142045   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50: 60nMAssay Description:Concentration required for inhibiting hepatitis C virus NS5B RNA polymerase activity.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50: 1.25E+5nMAssay Description:Concentration required to inhibit RNA dependent RNA polymerase was determined from polio virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-directed RNA polymerase subunit beta(Escherichia coli (strain K12))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50142045((S)-3-(5-Acetylamino-1H-indol-3-yl)-2-[(1-cyclohex...)
Affinity DataIC50: 2.50E+5nMAssay Description:Concentration required to inhibit DNA dependent RNA polymerase was determined from calf thymusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed