BDBM50141577 (2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL43087

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO

InChI Key InChIKey=WSWMIGCNSWBCNT-UHFFFAOYSA-N

Data  8 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50141577   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of heparin-binding HB-EGF sheddingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of human tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of recombinant human TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of human recombinant matrix metalloprotease 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of recombinant human matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  14nMAssay Description:Inhibition of recombinant human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  14nMAssay Description:Inhibition of human recombinant matrix metalloprotease 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  128nMAssay Description:Inhibition of human recombinant matrix metalloprotease 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Hokkaido Collaboration Center N-21

Curated by ChEMBL
LigandPNGBDBM50141577((2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-...)
Affinity DataKi:  128nMAssay Description:Inhibition of recombinant human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed