BDBM50141339 2-(3-tert-Butyl-ureido)-3-[4-(3-guanidino-benzoylamino)-phenyl]-propionic acid::CHEMBL417138

SMILES [#6]C([#6])([#6])[#7]-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(-[#7]-[#6](=O)-c2cccc(c2)\[#7]=[#6](/[#7])-[#7])cc1)-[#6](-[#8])=O

InChI Key InChIKey=MWLPKZBBCRIXMO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50141339   

TargetIntegrin alpha-V/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141339(2-(3-tert-Butyl-ureido)-3-[4-(3-guanidino-benzoyla...)
Affinity DataIC50: 4.80nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141339(2-(3-tert-Butyl-ureido)-3-[4-(3-guanidino-benzoyla...)
Affinity DataIC50: 285nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141339(2-(3-tert-Butyl-ureido)-3-[4-(3-guanidino-benzoyla...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141339(2-(3-tert-Butyl-ureido)-3-[4-(3-guanidino-benzoyla...)
Affinity DataIC50: 3nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141339(2-(3-tert-Butyl-ureido)-3-[4-(3-guanidino-benzoyla...)
Affinity DataIC50: 3.20nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed