BDBM50141313 2-Isopropoxycarbonylamino-3-{4-[3-(5-oxo-4,5-dihydro-1H-imidazol-2-ylamino)-benzoylamino]-phenyl}-propionic acid::CHEMBL37674

SMILES CC(C)OC(=O)NC(Cc1ccc(NC(=O)c2cccc(Nc3nc(O)c[nH]3)c2)cc1)C(O)=O

InChI Key InChIKey=BIAYEWRLSABXRF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50141313   

TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141313(2-Isopropoxycarbonylamino-3-{4-[3-(5-oxo-4,5-dihyd...)
Affinity DataIC50: 0.890nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141313(2-Isopropoxycarbonylamino-3-{4-[3-(5-oxo-4,5-dihyd...)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141313(2-Isopropoxycarbonylamino-3-{4-[3-(5-oxo-4,5-dihyd...)
Affinity DataIC50: 18nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141313(2-Isopropoxycarbonylamino-3-{4-[3-(5-oxo-4,5-dihyd...)
Affinity DataIC50: 0.940nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141313(2-Isopropoxycarbonylamino-3-{4-[3-(5-oxo-4,5-dihyd...)
Affinity DataIC50: 1.27E+3nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed