BDBM50141311 3-{4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-benzoylamino]-3,5-dimethyl-phenyl}-acrylic acid::CHEMBL37613

SMILES Cc1cc(C=CC(O)=O)cc(C)c1NC(=O)c1cccc(NC2=NCCN2)c1

InChI Key InChIKey=NGLDQEAARWHFFU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50141311   

TargetIntegrin alpha-V/beta-5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141311(3-{4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-benzoy...)
Affinity DataIC50: 29nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141311(3-{4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-benzoy...)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141311(3-{4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-benzoy...)
Affinity DataIC50: 264nMAssay Description:Binding affinity towards alpha V-beta1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141311(3-{4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-benzoy...)
Affinity DataIC50: 1.83E+3nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141311(3-{4-[3-(4,5-Dihydro-1H-imidazol-2-ylamino)-benzoy...)
Affinity DataIC50: 3nMAssay Description:Binding affinity towards alpha V-beta3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed