BDBM50141148 CHEMBL281467::N-[5-(3-Bromo-phenylamino)-6-cyano-[1,8]naphthyridin-3-yl]-acrylamide

SMILES Brc1cccc(Nc2c(cnc3ncc(NC(=O)C=C)cc23)C#N)c1

InChI Key InChIKey=NNPUTWBCLSJFPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141148   

TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141148(N-[5-(3-Bromo-phenylamino)-6-cyano-[1,8]naphthyrid...)
Affinity DataIC50: 975nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141148(N-[5-(3-Bromo-phenylamino)-6-cyano-[1,8]naphthyrid...)
Affinity DataIC50: 976nMAssay Description:Inhibition of epidermal growth factor receptor kinase autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed