BDBM50141111 CHEMBL3758901

SMILES ONC(=O)\C=C\c1ccc2OC3(CCN(Cc4ccccc4)C3)CC(=O)c2c1

InChI Key InChIKey=TWTUJMUGLFWIIG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50141111   

TargetHistone deacetylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50: 82nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50: 28nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50: 123nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50: 52nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50: 52nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50141111(CHEMBL3758901)
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC in human HeLa cells nuclear extract using Fluor de lys as substrate after 15 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed