BDBM50141083 6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-5,6,7,8-tetrahydro-naphthalen-1-yl}-pyridin-2-ylamine::CHEMBL416071

SMILES CN1CCN(CCOc2ccc(-c3cccc(N)n3)c3CCCCc23)CC1

InChI Key InChIKey=BMMQHMBKVRPTTF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141083   

TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141083(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-5,6,7,8-...)
Affinity DataIC50: 1.06E+4nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141083(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-5,6,7,8-...)
Affinity DataIC50: 1.28E+3nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141083(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-5,6,7,8-...)
Affinity DataIC50: 99.2nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141083(6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-5,6,7,8-...)
Affinity DataIC50: 121nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed