BDBM50141080 6-[4-(2-Dimethylamino-cyclohexyloxy)-naphthalen-1-yl]-pyridin-2-ylamine::CHEMBL41343

SMILES CN(C)C1CCCCC1Oc1ccc(-c2cccc(N)n2)c2ccccc12

InChI Key InChIKey=HAUBUNNZVAGIGM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141080   

TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141080(6-[4-(2-Dimethylamino-cyclohexyloxy)-naphthalen-1-...)
Affinity DataIC50: 2.37E+3nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141080(6-[4-(2-Dimethylamino-cyclohexyloxy)-naphthalen-1-...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141080(6-[4-(2-Dimethylamino-cyclohexyloxy)-naphthalen-1-...)
Affinity DataIC50: 140nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141080(6-[4-(2-Dimethylamino-cyclohexyloxy)-naphthalen-1-...)
Affinity DataIC50: 161nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed