BDBM50141017 2-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenylethynyl]-benzoic acid::CHEMBL34378

SMILES COc1ccc(cc1Cc1cnc(N)nc1N)C#Cc1ccccc1C(O)=O

InChI Key InChIKey=KOQCZRWUQXZQNK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141017   

TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141017(2-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductase of Toxoplasma gondiiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141017(2-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against dihydrofolate reductase of Mycobacterium aviumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141017(2-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration against dihydrofolate reductace enzyme of Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141017(2-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory concentration against dihydrofolate reductase of rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed