BDBM50140923 CHEMBL3753955

SMILES N#C\C(=C/c1cccnc1)c1c[nH]c2ccccc12

InChI Key InChIKey=YMYYQRZCCKBFBE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140923   

TargetKinesin-like protein KIF20A(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140923(CHEMBL3753955)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetKinesin-like protein KIF20A(Human)
Cnrs

Curated by ChEMBL
LigandPNGBDBM50140923(CHEMBL3753955)
Affinity DataIC50: 830nMAssay Description:Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
LigandPNGBDBM50140923(CHEMBL3753955)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50140923(CHEMBL3753955)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2018
Entry Details Article
PubMed
LigandPNGBDBM50140923(CHEMBL3753955)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed