BDBM50140670 (2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::CHEMBL24275

SMILES CC1(C)S[C@@H]2[C@@H](S)C(=O)N2[C@H]1C(O)=O

InChI Key InChIKey=WOYLBXUCZPJYOV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140670   

TargetMetallo-beta-lactamase L1 type 3(Pseudomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50: 3.69E+4nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50: 7.90E+3nMAssay Description:Beta-Lactamase inhibitory activity against represent active class C (P99) serine enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50: 9.88E+5nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140670((2S,5R,6S)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed