BDBM50140612 CHEMBL285573::methyl 5-ethyl-3-(4-methoxybenzyl)-4-oxo-(6aR,9aS)-3,4,5,8-tetrahydrocyclopenta[4,5]imidazo[2,1-b]purine-2-carboxylate

SMILES CCN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C(=O)OC)n(Cc3ccc(OC)cc3)c2C1=O

InChI Key InChIKey=PKJTVYVQDCERGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140612   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50140612(methyl 5-ethyl-3-(4-methoxybenzyl)-4-oxo-(6aR,9aS)...)
Affinity DataIC50: 6.80nMAssay Description:Inhibitory concentration against human phosphodiesterase 5 (PDE5) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50140612(methyl 5-ethyl-3-(4-methoxybenzyl)-4-oxo-(6aR,9aS)...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed