BDBM50140543 3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-5-fluoro-4-oxo-pentanoic acid::CHEMBL23226::Z-Val-Asp-fmk

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(O)=O)C(=O)CF

InChI Key InChIKey=LYBWGROBJJXCJJ-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50140543   

TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant caspase-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-8 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against the Calpain 1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against the Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCaspase-3(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against human recombinant Caspase-3 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCaspase-6(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 18nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-6 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCaspase-7(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 7nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-7 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCaspase-9(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 5nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-9 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCaspase-1(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 20nMAssay Description:Compound was evaluated for its inhibitory activity against the Caspase-1 enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against the ThrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Maxim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50140543(3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed