BDBM50140448 CHEMBL1579806

SMILES COc1ccc(CNc2ccc(cc2)S(N)(=O)=O)cc1

InChI Key InChIKey=AANJTRKLHIXTQA-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50140448   

TargetCarbonic anhydrase 2(Human)
Harran University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Harran University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Riga Technical University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  11nMAssay Description:Inhibition of human carbonic anhydrase 12 assessed as inhibition constant incubated for 1 hr prior to testing by phenol red based stopped-flow CO2 hy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Harran University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Riga Technical University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  427nMAssay Description:Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Harran University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  464nMAssay Description:Inhibition of human carbonic anhydrase 2 assessed as inhibition constant incubated for 1 hr prior to testing by phenol red based stopped-flow CO2 hyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Harran University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi:  883nMAssay Description:Inhibition of human carbonic anhydrase 9 assessed as inhibition constant incubated for 1 hr prior to testing by phenol red based stopped-flow CO2 hyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Harran University

Curated by ChEMBL
LigandPNGBDBM50140448(CHEMBL1579806)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 assessed as inhibition constant incubated for 1 hr prior to testing by phenol red based stopped-flow CO2 hyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed