BDBM50140318 (R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid::CHEMBL18883

SMILES C[C@@H](C(O)=O)c1ccc(C[C@@H]2CCC[C@H]2O)cc1

InChI Key InChIKey=SHAHPWSYJFYMRX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140318   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140318((R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory potency against Prostaglandin G/H synthase 1 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140318((R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory potency against cyclooxygenase-2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140318((R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50140318((R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against recombinant human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed