BDBM50140312 CHEMBL3754167

SMILES Nc1nc(cc(n1)-c1cccc(OC(=O)N2CCOCC2)c1)-c1ccccc1

InChI Key InChIKey=VIBAFZDZRHJJRN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140312   

TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50140312(CHEMBL3754167)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in Sprague-Dawley rat whole brain after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50140312(CHEMBL3754167)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]NECA from adenosine A2A receptor in Sprague-Dawley rat striatal membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50140312(CHEMBL3754167)
Affinity DataKi:  1.95E+3nMAssay Description:Binding affinity to human adenosine A2A receptor measured by radioligand-based affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50140312(CHEMBL3754167)
Affinity DataKi:  3.54E+3nMAssay Description:Binding affinity to human adenosine A1A receptor measured by radioligand-based affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed