BDBM50140231 5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid pyridin-4-ylamide::CHEMBL428693

SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)Nc1ccncc1

InChI Key InChIKey=PVMDOMHQDHYEFQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50140231   

TargetCannabinoid receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50140231(5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-meth...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-SR141716A from human CB1 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50140231(5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-meth...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50140231(5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-meth...)
Affinity DataKi:  85nMAssay Description:Evaluated for binding affinity towards human Cannabinoid receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50140231(5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-meth...)
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed