BDBM50140157 TRIACETYLRESVERATROL::US20240398793, Compound 4

SMILES CC(=O)Oc1ccc(\C=C\c2cc(OC(C)=O)cc(OC(C)=O)c2)cc1

InChI Key InChIKey=PDAYUJSOJIMKIS-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140157   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140157(TRIACETYLRESVERATROL | US20240398793, Compound 4)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140157(TRIACETYLRESVERATROL | US20240398793, Compound 4)
Affinity DataIC50: 1.18E+4nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level in presence of AITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140157(TRIACETYLRESVERATROL | US20240398793, Compound 4)
Affinity DataEC50:  7.50E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Celltaxis

US Patent
LigandPNGBDBM50140157(TRIACETYLRESVERATROL | US20240398793, Compound 4)
Affinity DataIC50: 3.86E+4nMAssay Description:The hydrolase-homogeneous time resolved fluorescence assay is a two-step assay that measures the hydrolysis of LTA4 to LTB4 by analyzing the amount o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

TargetTransthyretin(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50140157(TRIACETYLRESVERATROL | US20240398793, Compound 4)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of recombinant N-terminal hexa-histidine tagged TTR V30M mutant (unknown origin) expressed in Escherichia coli assessed as acid mediated a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed