BDBM50140156 CHEMBL2387062

SMILES COc1ccccc1\C=C\c1ccccc1

InChI Key InChIKey=FLQOKJWUYDGZIT-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140156   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140156(CHEMBL2387062)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced increase of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140156(CHEMBL2387062)
Affinity DataEC50:  880nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50140156(CHEMBL2387062)
Affinity DataIC50: 1.70E+3nMAssay Description:Agonist activity at rat TRPA1 expressed in HEK293 cells assessed as induction of intracellular calcium level in presence of AITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2017
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of New Mexico

Curated by ChEMBL
LigandPNGBDBM50140156(CHEMBL2387062)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HepG2 cells after 5 hrs by ARE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Human)
Hyogo University of Health Sciences

Curated by ChEMBL
LigandPNGBDBM50140156(CHEMBL2387062)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMed