BDBM50140044 CHEMBL3764353

SMILES Clc1ccc(CNC(=O)[C@H](CCCCNC2CC2c2ccccc2)NC(=O)c2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=VYCWLZJQGMLJOM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140044   

TargetLysine-specific histone demethylase 2(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50140044(CHEMBL3764353)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50140044(CHEMBL3764353)
Affinity DataIC50: 410nMAssay Description:Inhibition of human LSD1 using H3K4 peptide as substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50140044(CHEMBL3764353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate incubated for 1 hr by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50140044(CHEMBL3764353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using luminogenic MAO substrate incubated for 1 hr by lucife...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Waseda University

Curated by ChEMBL
LigandPNGBDBM50140044(CHEMBL3764353)
Affinity DataIC50: 410nMAssay Description:Inhibition of N-terminal His-tagged human LSD1 expressed in Escherichia coli using biotinylated H3K4Me2 peptide as substrate incubated for 60 min by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed