BDBM50139954 3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL14924

SMILES [#6]-[#8]-[#6](=O)-[#6]-1-[#6]-2-[#6]-[#6]-[#6](-[#6]-[#6]-1-c1ccc(\[#6]=[#6](/Br)Br)cc1)-[#7]-2-[#6]

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50139954   

TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50139954(3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-methyl-8-aza-bi...)
Affinity DataKi:  1.35nMAssay Description:Inhibition of [125I]RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50139954(3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-methyl-8-aza-bi...)
Affinity DataKi:  6.73nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]RTI-55 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50139954(3-[4-(2,2-Dibromo-vinyl)-phenyl]-8-methyl-8-aza-bi...)
Affinity DataKi:  161nMAssay Description:In vitro binding affinity against human norepinephrine transporter in human embryonic kidney cell line by using [125I]-RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed