BDBM50139927 CHEMBL3765741

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CCCCNC(=O)CNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCNC(N)=N)NC1=O

InChI Key InChIKey=PIOFOJDJMUUQDG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139927   

TargetMu-type opioid receptor(Human)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50139927(CHEMBL3765741)
Affinity DataIC50: 131nMAssay Description:Agonist activity at human MOR expressed in CHO cells assessed as induction of membrane potential change measured every 3 secs for 30 secs by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50139927(CHEMBL3765741)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]DAMGO from rat cortical MOR by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50139927(CHEMBL3765741)
Affinity DataKi:  8.53E+3nMAssay Description:Displacement of [3H]U69,593 from guinea pig KOR after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50139927(CHEMBL3765741)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from rat cortical DOR after 2.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed