BDBM50139824 7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chloride::CHEMBL367928

SMILES Oc1cc2cccc[n+]2c2cccc(Cl)c12

InChI Key InChIKey=RTLDJHACRZJMMP-UHFFFAOYSA-O

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139824   

LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50:  1.46E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 uM FskMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50: >2.00E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 uM FskMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50:  1.46E+5nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
LigandPNGBDBM50139824(7-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chl...)
Affinity DataEC50: >2.00E+5nMAssay Description:Activation of wildtype CFTR G551D mutant (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed