BDBM50139822 10-Chloro-6-hydroxy-pyrido[1,2-a]quinolinylium; chloride::CHEMBL175225
SMILES Oc1cc2cccc[n+]2c2c(Cl)cccc12
InChI Key InChIKey=FLJBLCAZPFDCPE-UHFFFAOYSA-O
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50139822
Affinity DataEC50: 1.41E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of wild type-CFTR activity in the presence of 10 uM FskMore data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+5nMAssay Description:Half-Maximal effective concentration of compound required to stimulate of G551D-CFTR activity in the presence of 10 uM FskMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of cyclin-dependent kinase 1 cdc2More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit alpha/beta/delta/gamma(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 7.60E+5nMAssay Description:Inhibition of [Ca(2+)]/Calmodulin dependent kinase IIMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of casein kinase IMore data for this Ligand-Target Pair
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Human)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of protein kinase CMore data for this Ligand-Target Pair
Affinity DataEC50: 1.41E+5nMAssay Description:Activation of wildtype CFTR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >2.00E+5nMAssay Description:Activation of wildtype CFTR G551D mutant (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair