BDBM50139650 CHEMBL3546834::US9688668, 50

SMILES CCCCCCCCc1ccc(cc1)-c1noc(n1)[C@H]1CCCN1C(N)=N

InChI Key InChIKey=JUZGDDYZTNXXNG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139650   

TargetSphingosine kinase 2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50139650(US9688668, 50 | CHEMBL3546834)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of recombinant SK2 (unknown origin) expressed in Sf9 cells assessed as [33P]S1P formation using D-erythro sphingosine as substrate and gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50139650(US9688668, 50 | CHEMBL3546834)
Affinity DataKi: >1.00E+4nMAssay Description:SphK activity was measured by a scintillation proximity assay as previously described [1], the disclosure of which is incorporated herein. Briefly, r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
Go to US Patent

TargetSphingosine kinase 2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50139650(US9688668, 50 | CHEMBL3546834)
Affinity DataKi: >1.00E+4nMAssay Description:SphK activity was measured by a scintillation proximity assay as previously described [1], the disclosure of which is incorporated herein. Briefly, r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2018
Entry Details
Go to US Patent

TargetSphingosine kinase 1(Human)
University of Virginia Patent Foundation

US Patent
LigandPNGBDBM50139650(US9688668, 50 | CHEMBL3546834)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of recombinant SK1 (unknown origin) expressed in Sf9 cells assessed as [33P]S1P formation using D-erythro sphingosine as substrate and gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2017
Entry Details Article
PubMed