BDBM50139312 CHEMBL160729::Furan-2-carboxylic acid [(R)-2-(4-{3-[3-fluoro-4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-phenoxy]-propyl}-piperazin-1-yl)-1-methyl-2-oxo-ethyl]-amide

SMILES C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(-c3noc(n3)-c3ccccc3)c(F)c2)CC1

InChI Key InChIKey=SSAVQTWNFLPIDN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139312   

TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139312(Furan-2-carboxylic acid [(R)-2-(4-{3-[3-fluoro-4-(...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for rat histamine H3 receptor on rat cortical cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139312(Furan-2-carboxylic acid [(R)-2-(4-{3-[3-fluoro-4-(...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity for rat histamine H3 receptor on rat cortical cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139312(Furan-2-carboxylic acid [(R)-2-(4-{3-[3-fluoro-4-(...)
Affinity DataKi:  43nMAssay Description:Binding affinity for human histamine H3 receptor on human colon cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139312(Furan-2-carboxylic acid [(R)-2-(4-{3-[3-fluoro-4-(...)
Affinity DataKi:  43nMAssay Description:Binding affinity for human histamine H3 receptor on human colon cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed