BDBM50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=XIJHWXXXIMEHKW-UHFFFAOYSA-N

Data  66 KI  42 IC50  17 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 125 hits for monomerid = 50139013   

TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50: >1.00E+3nMAssay Description:Antagonist activity at delta opioid receptor expressed in CHO cells assessed as release of intracellular calcium ions by aequorin luminescence-based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Medical University of Lodz

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50: >1.00E+3nMAssay Description:Activity at delta opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 24.1nMAssay Description:Inhibition of Mu opioid receptor of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 9.22nMAssay Description:Inhibition of Opioid receptor mu 1 of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from DOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in Dunkin Hartley guinea pig membranes by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from KOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H](Ile5,6)deltorphin-2 from DOR in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from MOR in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 48.2nMAssay Description:In vitro inhibitory concentration against Opioid receptor delta 1 was measured using mouse vas deferens assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 14.7nMAssay Description:In vitro inhibitory concentration against Opioid receptor mu 1 was measured using guinea pig ileum assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 344nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked muscle contractionsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 6.88nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig intestine assessed as inhibition of electrically evoked myenteric plexus longitudinal mu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells co-expressing C-terminally modified GGalphaqi5 assessed as stimulatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]nor-BNI from kappa opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 15nMAssay Description:Agonist activity at delta opioid receptor by inhibition of electrically evoked muscle contraction in isolated mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 7.70nMAssay Description:Agonist activity at mu opioid receptor by inhibition of electrically evoked muscle contraction in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  0.0400nMAssay Description:Activity at mu opioid receptor assessed as increase in calcium level in CHO cells by aequorin luminescence based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 6.90nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 344nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  0.0400nMAssay Description:Antagonist activity at mu opioid receptor expressed in CHO cells assessed as release of intracellular calcium ions by aequorin luminescence-based cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  78nMAssay Description:Activity at mu opioid receptor in Wistar rat brain assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 9.67nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 25.8nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human recombinant MOR expressed in CHO cells assessed as calcium mobilization by Fluo-4 AM based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.690nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin-2 from delta opioid receptor in Wistar rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.50E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 5.10E+5nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deference assessed as inhibition of electrically-stimulated contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 510nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically evoked contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 15nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 510nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 15nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  212nMAssay Description:Agonist activity at mu opioid receptor in rat brain membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 0.990nMAssay Description:Displacement of [3H]DAMGO from Wistar rat mu opioid receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin 2 from delta opioid receptor in Wistar rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 22nMAssay Description:Agonist activity at delta opioid receptor in Kunming mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 9.30nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 16.8nMAssay Description:Agonist activity at mu opioid receptor in NMRI mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 1.03E+4nMAssay Description:Displacement of [3H]deltorphin2 from delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 3.46nMAssay Description:Displacement of [3H]DAGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 14nMAssay Description:Agonist activity at mu opioid receptor by guinea pig ileum assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Biological Research Center of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataIC50: 13.7nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-evoked contraction of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataEC50:  383nMAssay Description:Agonist activity at mu opioid receptor in Wistar rat brain membranes after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
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