BDBM50138842 2,4-dimethylpentan-3-yl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate::CHEMBL84691::[(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester::[(S)-1-(4-Bromo-1H-pyrazol-3-ylaminooxalyl)-pentyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester

SMILES CCCC[C@H](NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=XZSGGBXVBKHOFH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50138842   

TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842([(S)-1-(4-Bromo-1H-pyrazol-3-ylaminooxalyl)-pentyl...)
Affinity DataIC50: 2.54nMAssay Description:Concentration required to inhibit 50% of cysteine protease cathepsin K of humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Rat)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842([(S)-1-(4-Bromo-1H-pyrazol-3-ylaminooxalyl)-pentyl...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against rat cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842([(S)-1-(4-Bromo-1H-pyrazol-3-ylaminooxalyl)-pentyl...)
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842([(S)-1-(4-Bromo-1H-pyrazol-3-ylaminooxalyl)-pentyl...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory concentration against recombinant human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50138842([(S)-1-(4-Bromo-1H-pyrazol-3-ylaminooxalyl)-pentyl...)
Affinity DataIC50: 2.51nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed