BDBM50138830 CHEMBL3752659::US10233190, Example 1415

SMILES O[C@H](C[C@@H]1c2ccccc2-c2cncn12)C1CCCCC1

InChI Key InChIKey=YTRRAUACYORZLX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50138830   

TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50138830(CHEMBL3752659 | US10233190, Example 1415)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in M15(pREP4) cells using L-tryptophan as substrate assessed as conversion of N-formylkynurenine to ky...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50138830(CHEMBL3752659 | US10233190, Example 1415)
Affinity DataIC50: 550nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50138830(CHEMBL3752659 | US10233190, Example 1415)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of purified human IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed