BDBM50138797 CHEMBL3752374

SMILES ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NC(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=HQCMGHWOKKWJEP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138797   

Target72 kDa type IV collagenase(Human)
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50138797(CHEMBL3752374)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50138797(CHEMBL3752374)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetElastase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50138797(CHEMBL3752374)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Uit The Arctic University of Norway

Curated by ChEMBL
LigandPNGBDBM50138797(CHEMBL3752374)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human ADAM17 after 30 mins using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed