BDBM50138752 5-Methylsulfanyl-3-((E)-styryl)-[1,2,4]triazole-1-carboxylic acid dimethylamide::CHEMBL339995::N,N-dimethyl-5-(methylthio)-3-styryl-1H-1,2,4-triazole-1-carboxamide

SMILES CSc1nc(\C=C\c2ccccc2)nn1C(=O)N(C)C

InChI Key InChIKey=ISTWOSNIZSCOAJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138752   

TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138752(N,N-dimethyl-5-(methylthio)-3-styryl-1H-1,2,4-tria...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138752(N,N-dimethyl-5-(methylthio)-3-styryl-1H-1,2,4-tria...)
Affinity DataIC50: 370nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138752(N,N-dimethyl-5-(methylthio)-3-styryl-1H-1,2,4-tria...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138752(N,N-dimethyl-5-(methylthio)-3-styryl-1H-1,2,4-tria...)
Affinity DataIC50: 882nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed