BDBM50138745 (3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazol-1-yl)(piperidin-1-yl)methanone::CHEMBL130666::[3-(4-Chloro-phenyl)-5-methylsulfanyl-[1,2,4]triazol-1-yl]-piperidin-1-yl-methanone

SMILES CSc1nc(nn1C(=O)N1CCCCC1)-c1ccc(Cl)cc1

InChI Key InChIKey=PBUOZLNZOBWRDT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138745   

TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50: 26nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50: 100nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138745((3-(4-chlorophenyl)-5-(methylthio)-1H-1,2,4-triazo...)
Affinity DataIC50: 1.76nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed