BDBM50138737 3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4]triazole-1-carboxylic acid methyl-phenyl-amide::3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trifluoroethylthio)-1H-1,2,4-triazole-1-carboxamide::CHEMBL131588

SMILES CN(C(=O)n1nc(nc1SCC(F)(F)F)-c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=LOFGEQLLLVJCDY-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50138737   

TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 170nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested to inhibit hepatic lipase (HL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLipoprotein lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested to inhibit lipoprotein lipase (LPL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138737(3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trif...)
Affinity DataIC50: 3nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed