BDBM50138732 3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4]triazole-1-carboxylic acid dimethylamide::CHEMBL131320::N,N-dimethyl-3-p-tolyl-5-(2,2,2-trifluoroethylthio)-1H-1,2,4-triazole-1-carboxamide

SMILES CN(C)C(=O)n1nc(nc1SCC(F)(F)F)-c1ccc(C)cc1

InChI Key InChIKey=MYAOJPWDGLEXIZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138732   

TargetCholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138732(3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4...)
Affinity DataIC50: 460nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138732(3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4...)
Affinity DataIC50: 600nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138732(3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHormone-sensitive lipase(Rat)
University of Jordan

Curated by ChEMBL
LigandPNGBDBM50138732(3-p-Tolyl-5-(2,2,2-trifluoro-ethylsulfanyl)-[1,2,4...)
Affinity DataIC50: 10.6nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed